Lixin Song Selected Research

Gamma Secretase Inhibitors and Modulators

1/2013	The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease.
1/2008	Solution-phase parallel synthesis of carbamates as gamma-secretase inhibitors.
11/2007	Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as gamma-secretase inhibitors.
1/2007	Discovery of gamma-secretase inhibitors efficacious in a transgenic animal model of Alzheimer's disease.
1/2007	Tetrahydroquinoline sulfonamides as gamma-secretase inhibitors.
1/2007	2,6-Disubstituted N-arylsulfonyl piperidines as gamma-secretase inhibitors.

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Lixin Song Research Topics

Disease

18	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 08/2003
7	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 08/2012
4	Neoplasms (Cancer) 06/2022 - 02/2018
2	Ulcer 07/2021 - 03/2021
2	Tauopathies 01/2020 - 01/2017
1	Corneal Ulcer 07/2021
1	Ocular Hypertension (Glaucoma, Suspect) 05/2021
1	Urinary Bladder Neoplasms (Bladder Cancer) 06/2020
1	Wounds and Injuries (Trauma) 06/2020
1	Stroke (Strokes) 10/2019
1	Hypertension (High Blood Pressure) 10/2019
1	Hot Flashes 01/2019
1	7 Hereditary Prostate Cancer 01/2019
1	Tonsillar Neoplasms 01/2018
1	Chronic Disease (Chronic Diseases) 01/2016
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2015
1	Pathologic Processes 03/2015
1	Thrombosis (Thrombus) 02/2014
1	Coinfection 03/2005
1	Amyloid Plaque 08/2003

Drug/Important Bio-Agent (IBA)

7	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2016 - 08/2003
6	Gamma Secretase Inhibitors and ModulatorsIBA 01/2013 - 01/2007
3	protein C activator peptideIBA 01/2022 - 08/2012
3	SCH 900229IBA 12/2016 - 11/2012
3	Amyloid (Amyloid Fibrils)IBA 11/2016 - 06/2011
2	ORALIT (ORS)IBA 09/2021 - 01/2019
2	hexosaminidase CIBA 01/2020 - 01/2017
2	CholesterolIBA 10/2019 - 01/2018
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2017 - 03/2015
2	Pharmaceutical PreparationsIBA 03/2015 - 01/2008
2	Peptides (Polypeptides)IBA 06/2011 - 08/2003
2	piperidineIBA 11/2007 - 01/2007
2	EnzymesIBA 03/2005 - 08/2003
1	Antineoplastic Agents (Antineoplastics)IBA 06/2022
1	Voriconazole (Vfend)FDA LinkGeneric 07/2021
1	Loteprednol Etabonate (Alrex)FDA Link 05/2021
1	prednisolone acetate FDA LinkGeneric 05/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2021
1	Ophthalmic Solutions (Eye Drops)IBA 05/2021
1	SuspensionsIBA 05/2021
1	Prostate-Specific Antigen (Semenogelase)IBA 11/2020
1	tau Proteins (tau Protein)IBA 01/2020
1	MedroxyprogesteroneIBA 01/2019
1	CyproteroneIBA 01/2019
1	AndrogensIBA 01/2019
1	Megestrol Acetate (Borea)FDA LinkGeneric 01/2019
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 03/2015
1	CarrageenanIBA 02/2014
1	SulfonesIBA 02/2013
1	Presenilin-1IBA 11/2012
1	MorpholinesIBA 11/2010
1	CarbamatesIBA 01/2008
1	1,2,3,4-tetrahydroquinolineIBA 01/2007
1	Flavin-Adenine Dinucleotide (FAD)IBA 03/2005

Therapy/Procedure

3	Therapeutics 08/2020 - 01/2016
1	Corneal Cross-Linking 07/2021
1	Transplantation 03/2021
1	Corneal Transplantation (Keratoplasty) 03/2021
1	Prostatectomy (Retropubic Prostatectomy) 01/2021
1	Ostomy 06/2020
1	Complementary Therapies (Alternative Medicine) 01/2019
1	Mediterranean Diet 01/2019
1	Dietary Approaches To Stop Hypertension 01/2019
1	Aftercare (After-Treatment) 02/2018
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2018
1	Oral Administration 11/2012